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Trogers base

Trogers base is a white solid organic compound, with a tetracyclic structure and formula of 2 CH 2. Trogers base and its analogs are soluble in various organic solvents and strong acidic aqueous solutions due to their protonation.





A cyclophane is a hydrocarbon consisting of an aromatic unit and an aliphatic chain that forms a bridge between two non-adjacent positions of the aromatic ring. More complex derivatives with multiple aromatic units and bridges forming cagelike st ...





The macrolides are a class of natural products that consist of a large macrocyclic lactone ring to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The lactone rings are usually 14-, 15-, or 16-membered. Macrolid ...


Halichondrin B

Halichondrin B is a large naturally occurring polyether macrolide originally isolated from the marine sponge Halichondria okadai by Hirata and Uemura in 1986. In the same report, these authors also reported the exquisite anticancer activity of ha ...



Mepartricin is a macrolide polyene compound that is useful for urethra, prostate, and bladder function. It has been studied for use in treating chronic pelvic pain syndrome and benign prostatic hyperplasia.



Mitemcinal is a motilin agonist derived from the macrolide antibiotic, erythromycin. It was discovered in the labs of Chugai Pharma. Mitemcinal is orally administered and it is believed to have strong promotility effects. Promotility drugs reliev ...



Ridaforolimus is an investigational targeted and small-molecule inhibitor of the protein mTOR, a protein that acts as a central regulator of protein synthesis, cell proliferation, cell cycle progression and cell survival, integrating signals from ...



Umirolimus is an immunosuppressant, a macrocyclic lactone, a highly lipophilic derivative of sirolimus. This drug is proprietary to Biosensors International, which uses it in its own drug-eluting stents, and licenses it to partners such as Terumo ...



Tetrapyrroles are a class of chemical compounds that contain four pyrrole or pyrrole-like rings. The pyrrole/pyrrole derivatives are linked by - or - CH 2 - units), in either a linear or a cyclic fashion. Pyrroles are a five-atom ring with four c ...



Dihydrosirohydrochlorin is one of several naturally occurring tetrapyrrole macrocyclic metabolic intermediates in the biosynthesis of vitamin B 12. Its oxidised form, sirohydrochlorin, is precursor to sirohaem, the iron-containing prosthetic grou ...



Hydroxymethylbilane, also known as preuroporphyrinogen, is an organic compound that occurs in living organisms during the synthesis of porphyrins, a group of critical substances that include hemoglobin, myoglobin, and chorophyll. The name is ofte ...



In biochemistry a porphyrinogen is a member of a class of naturally occurring compounds with a tetrapyrrole core, a macrocycle of four pyrrole rings connected by four methylene bridges. They can be viewed as derived from the parent compound hexah ...



Sirohydrochlorin is a tetrapyrrole macrocyclic metabolic intermediate in the biosynthesis of sirohaem, the iron-containing prosthetic group in sulfite reductase enzymes. It is also the biosynthetic precursor to cofactor F430, an enzyme which cata ...


Uroporphyrinogen I

Uroporphyrinogen I is an isomer of uroporphyrinogen III, a metabolic intermediate in the biosynthesis of heme. A type of porphyria is caused by production of uroporphyrinogen I instead of III.


Uroporphyrinogen III

Uroporphyrinogen III is a tetrapyrrole, the first macrocyclic intermediate in the biosynthesis of heme, chlorophyll, vitamin B12, and siroheme. It is a colorless compound, like other porphyrinogens.





Bicyclodecapentaene is a bicyclic organic compound and an isomer of naphthalene and azulene. Whether this substance is an aromatic compound is of interest to researchers. Both the component cyclobutadiene and cyclooctatetraene component rings are ...



Octalene can be readily reduced by lithium to a di-anion C 14 H 12 2- and, unusually for such a small molecule, a tetra-anion C 14 H 12 4-. The di-anion has its two negative charges in one ring, converting that ring into a 10-pi electron aromatic ...



Oxanorbornadiene is a bicyclic organic compound with an oxygen atom bridging the two opposing saturated carbons of 1.4-cyclohexadiene. OND is related to all-carbon bicycle norbornadiene.







Iceane is a saturated polycyclic hydrocarbon with formula C 12 H 18. It has a cage-like molecular structure, whose carbon skeleton can be viewed as three fused cyclohexane rings in the boat conformation; or as two such rings in the chair conforma ...



Oleanane is a natural triterpenoid. It is commonly found in woody angiosperms and as a result is often used as an indicator of these plants in the fossil record. It is a member of the oleanoid series, which consists of pentacyclic triterpenoids w ...



Twistane is an organic compound with the formula C 10 H 16. It is a cycloalkane and an isomer of the simplest diamondoid, adamantane, and like adamantane, is not very volatile. Twistane was named for the way its rings are permanently forced into ...



Tetracyclics are chemical compounds that contain four interconnected rings of atoms, e.g. Trogers base. They have various pharmaceutical uses, for instance the tetracycline antibiotics and the tetracyclic antidepressants.






Disulfur dichloride

Disulfur dichloride is the inorganic compound of sulfur and chlorine with the formula S 2 Cl 2. Some alternative names for this compound are sulfur monochloride the name implied by its empirical formula, SCl, disulphur dichloride British English ...


Sulfur dichloride

Sulfur dichloride is the chemical compound with the formula SCl 2. This cherry-red liquid is the simplest sulfur chloride and one of the most common. It is used as a precursor to organosulfur compounds.


Dimethylthiocarbamoyl chloride

Dimethylthiocarbamoyl chloride is an organosulfur compound with the formula 2 NCCl. A yellow solid, it is often encountered as a yellow syrup. It is a key reagent in the synthesis of arylthiols via the Newman-Kwart rearrangement.



1.3-Difluoro-trisulfane-1.1-difluoride is an inorganic molecular substance consisting of sulfur in a low oxidation state with fluorine. The structural formula is SF 3 SSF containing a chain of three sulfur atoms. At one end there are three fluori ...



An interhalogen compound is a molecule which contains two or more different halogen atoms and no atoms of elements from any other group. Most interhalogen compounds known are binary composed of only two distinct elements. Their formulae are gener ...



Chloramines refer to derivatives of ammonia and organic amines wherein one or more N-H bonds have been replaced by N-Cl bonds. Two classes of compounds are considered, inorganic chloramines and organic chloramines.


Phosphoryl chloride difluoride

Phosphoric chloride difluoride POF 2 Cl is a colourless gas. At one atmosphere pressure the gas condenses to a liquid at 3.1°C and freezes at −96.4. Alternate names are difluorophosphoryl chloride or phosphoryl chloride difluoride.


Silicon carbide fibers

Silicon carbide fibers range from 5–150 micrometres in diameter and composed primarily of silicon carbide molecules. Depending on manufacturing process, they may have some excess silicon or carbon, or have a small amount of oxygen. Relative to or ...





Not to be confused with tetrazine or tetracene or tetrazene explosive Tetrazene is a chemical compound with the molecular formula N 4 H 4. In IUPAC nomenclature, derivatives of this compound are known collectively as tetrazenes. The most common o ...



Triazene is an unsaturated inorganic compound having the chemical formula N 3 H 3. It has one double bond, and is the second-simplest member of the azene class of hydronitrogen compounds after diimide. Triazenes are a class of organic compounds c ...


Nitroxylic acid

Nitroxylic acid or hydronitrous acid is an unstable reduced oxonitrogen acid. It has formula H 4 N 2 O 4 containing nitrogen in the +2 oxidation state. The corresponding anion called nitroxylate is N 2 O 4− 4 or NO 2− 2. The first clue that nitro ...



Diphosphane is an inorganic compound with the chemical formula P 2 H 4. This colourless liquid is one of several binary phosphorus hydrides. It is the impurity that typically causes samples of phosphine to ignite in air. An older name is diphosphine.



Triphosphane or triphosphine is an inorganic compound having the chemical formula HP 2. It can be generated from diphosphine but is highly unstable at room temperature: 2 P 2 H 4 → P 3 H 5 + PH 3 Samples to date have been contaminated with P 2 H ...


Amyl alcohol

An amyl alcohol is any of 8 alcohols with the formula C 5 H 12 O. A mixture of amyl alcohols can be obtained from fusel alcohol. Amyl alcohol is used as a solvent and in esterfication, by which is produced amyl acetate and other important product ...



1-Heptanol is an alcohol with a seven carbon chain and the structural formula of CH 3 6 OH. It is a clear colorless liquid that is very slightly soluble in water, but miscible with ether and ethanol.


Isoamyl alcohol

Isoamyl alcohol is a colorless liquid with the formula 2 CHCH 2 CH 2 OH. It is one of several isomers of amyl alcohol. It is an ingredient in the production of banana oil, an ester found in nature and also produced as a flavouring in industry. It ...





2-Propylheptanol is an oxo alcohol, meaning that it is produced from the hydroformylation "oxo synthesis" of C4 alkenes followed by hydrogenation of the resulting aldehyde. The production route is similar to that for 2-Ethylhexanol.

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